frameshift mutagen

frame·shift mu·ta·gen

a mutagen, such as an acridine derivative, that causes a reading-frame-shift mutation; codons (base triplets) are read out of phase and different amino acids are used.
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
In our experiment performed with AO, a known frameshift mutagen, which acts by virtue of its intercalative DNA-binding ability (Ferguson and Denny, 1991), the concentration-dependent inhibitory effect of 1s, 2s and 3s was observed.
Triterpenoid cynarasaponins from Cynara cardunculus L. reduce chemically induced mutagenesis in vitro
These strains were TA 98 and TA 1537, which primarily respond to frameshift mutagens, and TA 100, TA 102 and TA 1535, which respond to base-pair substitution mutagens.
Assessment of genotoxicity of herbal medicinal products: application of the "bracketing and matrixing" concept using the example of Valerianae radix (valerian root)
Carcinogens as frameshift mutagens: metabolites and derivatives of 2-acetylaminofluorene and other aromatic amine carcinogens.
The Salmonella mutagenicity assay: the stethoscope of genetic toxicology for the 21st Century
Medical browser ?
Full browser ?